Myxothiazol, a new antibiotic interfering with respiration

Abstract
Myxothiazol, a new antibiotic from the myxobacterium Myxococcus fulvus, inhibited the growth of mnay yeasts and fungi at concentrations between 0.01-3 .mu.g/ml. It was generally inactive against bacteria. The inhibitory effect was cytostatic. With Candida albicans, Saccharomyces cerevisiae and Mucor hiemalis, the growth inhibition was neutralized by glucose. Soon after being added to a cell suspension, the compound almost completely blocked O2 consumption.