A Simplex Optimized Colorimetric Method for Formaldehyde

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Abstract
The development of a rapid and precise method for analyzing formaldehyde is described. By using an experiment design technique known as simplex optimization, the sensitivity for this procedure was maximized. The analysis requires under 2 minutes of the analyst's time per sample and gives an average coefficient of variation of 1.3 percent. The average sensitivity is 0.294 A/μg/ml and as little as 0.018 μg/ml can be detected with 90 percent confidence if triplicate analyses are performed.