Blood 5-hydroxytryptamine levels in the newborn.
Open Access
- 1 October 1965
- journal article
- research article
- Published by BMJ in Archives of Disease in Childhood
- Vol. 40 (213) , 513-515
- https://doi.org/10.1136/adc.40.213.513
Abstract
Whole blood 5-hydroxytryptamine (5HT) levels, determined in a series of normal full-term infants, were low at birth (21 [plus or minus] 13 m[mu]g/ml) but rose to adult concentrations (162 [plus or minus] 64 m[mu]g/ml) by 4-6 weeks of life, though blood platelet counts remained unchanged. These findings are likely to be connected with the maturation of enzymes responsible for 5-hydroxytryptamine synthesis.This publication has 18 references indexed in Scilit:
- The estimation of 5-hydroxytryptamine in human bloodBiochemical Pharmacology, 1964
- Concentration of 5-hydroxytryptamine in the small intestine and platelets of the developing guinea pigBiochemical Pharmacology, 1964
- Mechanisms for the Decrease of Brain SerotoninNature, 1963
- Serotonin in the Developing MammalThe Journal of general physiology, 1962
- 5-HYDROXYINDOLES IN MENTAL DEFICIENCYJournal of Neurology, Neurosurgery & Psychiatry, 1960
- AMINE OXIDASE AND 5‐HYDROXYTRYPTAMINE IN DEVELOPING RAT BRAINJournal of Neurochemistry, 1960
- Development of 5-Hydroxytryptophan Decarboxylase Activity in Rat KidneyNature, 1960
- Serotonin content of rat brain in relation to sex and ageJournal of Neurochemistry, 1960
- Histochemical Study of Monoamine Oxidase in the Developing Rat BrainNature, 1959
- HISTAMINE AND 5-HYDROXYTRYPTAMINE IN THE BLOOD OF INFANTS AND CHILDRENJournal of Clinical Investigation, 1959