New congeners of swinholides from the okinawan marine sponge Theonella sp.

Abstract
Four new cytotoxic dimeric macrolides, swinholides D–G and a monomeric seco acid of swinholide A have been isolated from the Okinawan marine sponge Theonella sp. together with known macrodiolides, swinholides A and B and isoswinholide A and the structures elucidated on the basis of spectroscopic data.

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