[Detection and analysis of SARS coronavirus-specific antibodies in sera from non-SARS children].

  • 1 October 2003
    • journal article
    • abstracts
    • Vol. 23  (10) , 1085-7
Abstract
To examine the presence of severe acute respiratory syndrome (SARS) coronavirus-specific antibodies in the sera from non-SARS children. Indirect immunofluorescent assay and double-antigen sandwich enzyme-linked immunosorbent assay (ELISA) were used to detect the virus-specific antibodies in sera of 1,060 non-SARS children in Guangzhou. All the serum samples from the 1,060 non-SARS children were negative for both IgG and IgM antibodies against SARS coronavirus as determined by indirect immunofluorescent assay, with only two serum samples showing weak positivity for SARS coronavirus-specific antibodies identified by double-antigen sandwich ELISA. No SARS coronavirus-specific antibody are present in the sera of non-SARS children.

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