TISSUE-CULTURE OF CELLS IN SEROUS EFFUSIONS EVALUATION AS AN ADJUNCT TO CYTOLOGY

  • 1 January 1978
    • journal article
    • research article
    • Vol. 22  (6) , 487-489
Abstract
Cell pellets from peritoneal, pleural and pericardial effusions from 36 patients were incubated in tissue culture medium. Both the culture supernatants and the cell monalayers in the flasks were examined for malignant cells. Of the 10 cases diagnosed as positive for malignant cells by the conventional cytologic smears, 8 were positive on examination of the tissue culture supernatants and only 6 were positive by analysis of the monolayers. All the cases diagnosed as positive from the culture supernatants and from the monolayers were also positive by the conventional smear method. Tissue culture of cells in serous effusions is not helpful as an adjunct to routine diagnostic cytology techniques.

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