THE EFFECT OF GLUTARALDEHYDE ON THE STABILITY OF ERYTHROCYTES AND ON VIRUS RECEPTOR SUBSTANCES
- 15 August 2009
- journal article
- research article
- Published by Wiley in Acta Pathologica Microbiologica Scandinavica Section B Microbiology
- Vol. 84B (4) , 196-200
- https://doi.org/10.1111/j.1699-0463.1976.tb01925.x
Abstract
Fixation with glutaraldehyde at a concentration above 0.05% for 1 h at neutrality rendered erythrocytes [human and animal] resistant towards surfactants at Triton X-100, Tween-80 and sodium dodecyl sulfate. Fixation of erythrocytes with low concentrations of glutaraldehyde abolished the lytic effect of membrane active proteins as complement, phospholipase C and staphylococcal .alpha.-toxin. The fixation procedure did not alter significantly the receptor groups on erythocytes for viruses of the ortho- and para-myxo group and rubella virus. The fixation reduced the agglutinability of human O-erythrocytes by reovirus.Keywords
This publication has 6 references indexed in Scilit:
- Inactivation of Enterovirus by GlutaraldehydeApplied Microbiology, 1975
- Effect of Glutaraldehyde on Cell Viability, Triphenyltetrazolium Reduction, Oxygen Uptake, and β-Galactosidase Activity in Escherichia coliApplied Microbiology, 1973
- Glutaraldehyde, cyanuric choloride and tetraazotiexe O-dianisidine as coupling reagents in the passive hemagglutination testImmunochemistry, 1969
- The Cross-linking of Proteins with Glutaraldehyde and its use for the preparation of immunoadsorbentsImmunochemistry, 1969
- Coupling of enzymes to proteins with glutaraldehydeImmunochemistry, 1969
- Hemagglutination with reovirusesVirology, 1963