Cardiovascular effects of paroxetine
- 1 November 1990
- journal article
- research article
- Published by Springer Nature in Psychopharmacology
- Vol. 102 (3) , 379-382
- https://doi.org/10.1007/bf02244107
Abstract
In a double-blind clinical study, electrocardiogram, blood pressure and systolic time intervals were measured in 40 depressive patients treated with either paroxetine (30 mg/day) or amitriptyline (150 mg/day) for 6 weeks. While amitriptyline significantly increased the heart rate, the QTc interval and the PEP/LVET ratio, paroxetine did not alter any of the cardiovascular parameters measured.Keywords
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