Failure of Antiviral Therapy for Acquired Immunodeficiency Syndrome-Related Cytomegalovirus Myelitis
- 1 October 1988
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 45 (10) , 1090-1092
- https://doi.org/10.1001/archneur.1988.00520340044009
Abstract
• We report the first published case (to our knowledge) of histopathologically documented acquired immunodeficiency syndrome-related cytomegalovirus (CMV) myelitis in which antiviral drug therapy was administered. Despite sensitivity of the patient's CMV isolate to therapy with both ganciclovir and foscarnet, use of neither of these agents halted progression of central nervous system CMV disease. Higher doses of these drugs or combination therapy may be required to treat acquired immunodeficiency syndrome-related CMV myelitis effectively.This publication has 1 reference indexed in Scilit: