Is pK OK?
- 8 April 1982
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 306 (14) , 864-866
- https://doi.org/10.1056/nejm198204083061410
Abstract
Since Hasselbalch1 introduced his logarithmic form of Henderson's2 equation (pH = pK′ + log HC03-/αPC02) it has been used to define the acid–base status of patients by providing the means for the calculation of one of the three variables — pH, carbon dioxide tension (PC02), or bicarbonate concentration (HCO3- ) — from knowledge of the other two. In most clinical laboratories today, pH and PC02 are measured, and HC03- is calculated from the equation. However, there are pitfalls inherent in this use of the equation. It is often forgotten that the . . .Keywords
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