A Tomato Cysteine Protease Required for Cf-2 -Dependent Disease Resistance and Suppression of Autonecrosis
- 26 April 2002
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 296 (5568) , 744-747
- https://doi.org/10.1126/science.1069288
Abstract
Little is known of how plant disease resistance (R) proteins recognize pathogens and activate plant defenses. Rcr3 is specifically required for the function of Cf-2, aLycopersicon pimpinellifolium gene bred into cultivated tomato (Lycopersicon esculentum) for resistance toCladosporium fulvum. Rcr3 encodes a secreted papain-like cysteine endoprotease. Genetic analysis shows Rcr3 is allelic to the L. pimpinellifolium Ne gene, which suppresses the Cf-2–dependent autonecrosis conditioned by its L. esculentum allele, ne (necrosis).Rcr3 alleles from these two species encode proteins that differ by only seven amino acids. Possible roles of Rcr3 in Cf-2–dependent defense and autonecrosis are discussed.Keywords
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