Myocardial Oxygen Consumption, Left Ventricular Fibre Shortening and Wall Tension
- 1 July 1967
- journal article
- research article
- Published by Oxford University Press (OUP) in Cardiovascular Research
- Vol. 1 (3) , 219-228
- https://doi.org/10.1093/cvr/1.3.219
Abstract
Myocardial oxygen consumption (MVO2) was studied in a canine right heart bypass preparation. At constant heart rate and left ventricular peak developed tension (calculated from ventricular volume and pressure), doubling cardiac inflow increased MVO2 by 1·3 ml./100 g LV/min. This approximate 10% increase is attributed to increased contractile element shortening and work.Keywords
This publication has 33 references indexed in Scilit:
- Studies on digitalis. XVI. Effects on myocardial oxygen consumption.Journal of Clinical Investigation, 1966
- Isoproterenol and cardiovascular performanceThe American Journal of Medicine, 1964
- Contractile Element Work: A Major Determinant of Myocardial Oxygen Consumption*Journal of Clinical Investigation, 1964
- The variation of total heat production in a twitch with velocity of shorteningProceedings of the Royal Society of London. B. Biological Sciences, 1964
- Fundamental Concepts of Cardiac Dynamics and EnergeticsAnnual Review of Medicine, 1963
- Left Ventricular Pressure -Volume Relationships and Myocardial Oxygen Consumption in the Isolated HeartCirculation Research, 1961
- A STUDY OF INOTROPIC MECHANISMS IN THE PAPILLARY MUSCLE PREPARATIONThe Journal of general physiology, 1959
- Work and heat in a muscle twitchProceedings of the Royal Society of London. B. Biological Sciences, 1949
- The energetics of relaxation in a muscle twitchProceedings of the Royal Society of London. B. Biological Sciences, 1949
- The heat of shortening and the dynamic constants of muscleProceedings of the Royal Society of London. B. Biological Sciences, 1938