Levan Production by a Strain of Rothia: Activation of Complement Resulting in Cytotoxicity for Human Gingival Cells
- 1 September 1977
- journal article
- research article
- Published by SAGE Publications in Journal of Dental Research
- Vol. 56 (9) , 1097-1105
- https://doi.org/10.1177/00220345770560091401
Abstract
An extracellular polysaccharide identified as a levan has been isolated from Rothia dentocariosa, strain 477 serotype 2. The levan produced by strain 477 has been found to activate the complement cascade in the absence of specific antibodies. This activation was found to be cytotoxic for human gingival cells in tissue culture.Keywords
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