Precipitating factors in respiratory allergic disease in Indonesian children

Abstract
Skin test results and Ig[immunoglobulin]E antibody levels measured by the RAST [radioallergosorbent test] indicate that hypersensitivity to house dust mite (Dermatophagoides pteronyssinus) is a major feature of asthma and allergic rhinitis in Indonesian children. Total serum IgE levels were higher in the allergic than in control children. Sixty percent (21 of 35) of the asthmatic children and 56% (5 of 9) of the children with allergic rhinitis had IgE antibodies to the helminth Ascaris lumbricoides compared with none out of 4 control children. A tendency was found for high IgE antibody levels to D. pteronyssinus to occur in association with low IgE antibody levels to A. lumbricoides and vice versa.

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