Abstract
The epithelial cells of the posterior intestine of the rainbow trout differentiate some structures which, at the first feeding, allow the absorbtion of macromolecular proteins. After a transit across an apical tubulo-vesicular network, two marker proteins (horseradish peroxidase and ferritin) are segregated within an important supranuclear vacuolar system. The activities of a lysosomal protease (cathepsin) and of acid phosphatase increase strongly at the level of posterior intestine when the first feeding occurs. Juveniles can thus absorb and digest macromolecular proteins. Considering the important protein needs during this phase, this process can be of fundamental importance.