From Induced Fit to Conformational Selection: A Continuum of Binding Mechanism Controlled by the Timescale of Conformational Transitions
- 1 March 2010
- journal article
- research article
- Published by Elsevier in Biophysical Journal
- Vol. 98 (6) , L15-L17
- https://doi.org/10.1016/j.bpj.2009.11.029
Abstract
No abstract availableKeywords
This publication has 13 references indexed in Scilit:
- Conformational selection or induced fit: A flux description of reaction mechanismProceedings of the National Academy of Sciences, 2009
- Mechanism of Ligand-Induced Folding of a Natively Unfolded Helixless Variant of Rabbit I-BABPBiochemistry, 2009
- Reconciling binding mechanisms of intrinsically disordered proteinsBiochemical and Biophysical Research Communications, 2009
- NMR Chemical Exchange as a Probe for Ligand-Binding Kinetics in a Theophylline-Binding RNA AptamerJournal of the American Chemical Society, 2009
- Substrate Induced Population Shifts and Stochastic Gating in the PBCV-1 mRNA Capping EnzymeJournal of the American Chemical Society, 2009
- Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selectionProceedings of the National Academy of Sciences, 2008
- Dynamic energy landscape view of coupled binding and protein conformational change: Induced-fit versus population-shift mechanismsProceedings of the National Academy of Sciences, 2008
- Probing the mechanism of recognition of ssDNA by the Cdc13-DBDNucleic Acids Research, 2008
- Investigation of Ligand Binding and Protein Dynamics in Bacillus subtilis Chorismate Mutase by Transverse Relaxation Optimized Spectroscopy−Nuclear Magnetic Resonance,Biochemistry, 2005
- A diffusion Michaelis-Menten mechanism: Continuous conformational change in enzymatic kineticsJournal of Theoretical Biology, 1985