Vascular clearance of blastospore and pseudomycelial phaseCandida albicans
- 1 January 1977
- journal article
- research article
- Published by Oxford University Press (OUP) in Medical Mycology
- Vol. 15 (2) , 201-205
- https://doi.org/10.1080/00362177785190301
Abstract
Blastospore phase and pseudomycelial phase Candida albicans were infused at a constant rate into the proximal aorta of rabbits and simultaneous quantitative blood cultures were obtained from the abdominal aorta and inferior vena cava. Arteriovenous differences were greater with pseudomycelial phase C. albicans at all concentrations tested. Rates of clearance of C. albicans as blastospores or with pseudomycelia yielded mean T one-half values of 22 seconds and 17 seconds, respectively. Similarly, hepatic clearance of pseudomycelial phase C. albicans was more efficient. Prior immunization with heat-killed Candida albicans had no effect on the vascular clearance of either pseudomycelial phase or blastospore phase C. albicans. La phase blastosporique et pseudomycélien de Candida albicans a été infusé dans proximal aorte du lapin avec la rapidité constante. Simultanément les cultures quantitative du sang ont été pris de l'aortel abdominal et de la veine cave inférieure. Nous avons observé, que la différence parmi le sang artérie et veineux est plus accentué pendant la phase pseudomycélien de C. albicans, dans tous concentrations investigés. La disparition hepatique de psudomycelium phase de C. albicans a été beaucoup plus efficace. Après l'immunization avec C. albicans, tuée par chaleur, nous n'avons pas observé l'action vasculaire de la disparition avec la phase de pseudomycélien ou blastosporique de C. albicans.This publication has 9 references indexed in Scilit:
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