MATERIAL During the past sixteen years, from 1930 to 1945, inclusive, a total of 219 patients with malignant disease of either the nose or the nasal accessory sinuses, or a combination of both, were seen at the Massachusetts Eye and Ear Infirmary. These cases were studied, the diagnosis made by biopsy, and treatment given in the Infirmary, in the X-Ray Department of the Massachusetts General Hospital, or in both, and the cases were followed by the otolaryngological staff in the Tumor Clinic of the Massachusetts General Hospital. A recent survey1reveals that among these 219 cases there were 139 males and 80 females. The average age was 56 years, the youngest patient being 16 and the oldest 83 years of age. Among the 219 cases there were 10 untraced and 62 (30 per cent) with a five year survival or longer. The relation of the treatment to the survival