Some Interrelations of Drug and Ion Actions in the Artificial Activation of Marine Eggs

Publisher Website
Google Scholar
Abstract
Eggs of Urechis caupo were activated by brief treatment with a modified artificial sea water containing Na+ as the only cat-ion ; longer treatment led to cytolysis. Addition of cations other than Na retarded or prevented activation, with 2 ex-ceptions. High concs. of K+ increased the rate of activa-tion slightly and retarded cytolysis, while low or moderate concs. of Ca++ often increased the rate of activation very markedly. The effect of Ca++ was increased by high concs. of K+, decreased by lower concs. of K+, and entirely abol-ished by acetylcholine (1/104). Acetylcholine, choline, ad-renaline, pilocarpine, arecoline and histamine (1/104) in-hibited activation by ultraviolet; acetylcholine in lower conc. (< 1/106) increased activation by u.-v. Nicotine (1/104) activated the eggs.
Keywords

This publication has 29 references indexed in Scilit: