A new start in Madrid
Open Access
- 1 August 2002
- journal article
- research article
- Published by European Molecular Biology Organization in EMBO Reports
- Vol. 3 (8) , 718-723
- https://doi.org/10.1093/embo-reports/kvf162
Abstract
This symposium, held on February 6–9, 2002, marked the scientific opening of the Centro Nacional de Investigaciones Oncológicals(Spanish National Cancer Centre). The first national institute in Spain to focus on basis and applied cancer research will organize four conferences each year, covering different aspects of cancer research. These meetings, limited to a total of 20–25 speakers and an equal number of participants, should provide an ideas and scientific information surrounding topics of current interest. This first symposium brought together 160 participants including basic researches and clinicians, who all thoroughly enjoyed the scientific and social opportunities. ![][1] Without doubt, the sequencing of the human and other important genomes has paved the way for the revolution in biology and medicine that we are experiencing today. Decoding this information in terms of regulation and function (functional genomics) is high on the agendas of governments and funding agencies and is expected to dominate research in the life sciences in the early part of this century. We are moving rapidly from the study of single molecules to the analysis of complex biological processes, and the current explosion of new and powerful technologies promises to accelerate the application of basic discoveries into daily clinical practice. Cancer affects a significant proportion of the population and has become a prime focus for these new technologies. Indeed, tools for the high‐throughput analysis of genes, proteins and their complex networks are being used to identify potential targets for drug discovery and to uncover markers for early detection, recurrence, progression and response to treatment, as well as to develop novel therapies. Molecules being currently investigated include cell‐cycle regulators, growth factors, angiogenesis factors and signal transducing proteins, as well as components of apoptosis and DNA repair pathways. The purpose of the first symposium of the Centro Nacional de Investigaciones Oncológicas (CNIO) was to … [1]: pending:yesKeywords
This publication has 8 references indexed in Scilit:
- Modulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extensionThe Journal of cell biology, 2002
- p14ARF nuclear overexpression in aggressive B-cell lymphomas is a sensor of malfunction of the common tumor suppressor pathwaysBlood, 2002
- Identification of a Candidate Tumor-Suppressor Gene Specifically Activated during Ras-Induced SenescenceExperimental Cell Research, 2002
- Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genesGenes & Development, 2001
- Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumoursThe Journal of Pathology, 2001
- Phosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated and is required for G 1 /S checkpoint activation in response to DNA damageProceedings of the National Academy of Sciences, 2001
- Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytesThe EMBO Journal, 2001
- Skin abnormalities generated by temporally controlled RXRα mutations in mouse epidermisNature, 2000