Trisomy 8 in the Chronic Phase of Philadelphia Negative Chronic Myelocytic Leukaemia

Abstract
An unusual case of Philadelphia negative chronic myelocytic leukemia and an extra chromosome 8 in all bone marrow cells is described. The abnormality was present at diagnosis of the disease and throughout the chronic phase which lasted for somewhat less than 2 yr. The patient died soon after blastic transformation with no other chromosomal abnormalities.