ARTHRITIS IN MEDITERRANEAN SPOTTED FEVER. AN IMMUNE COMPLEX MEDIATED SYNOVITIS
- 1 July 1993
- journal article
- case report
- Published by Oxford University Press (OUP) in Rheumatology
- Vol. 32 (7) , 642-643
- https://doi.org/10.1093/rheumatology/32.7.642
Abstract
Arthromyalgia are frequent in Mediterranean spotted fever (MSF) (16–76%) but arthritis is rare. We report on a 54-year-old woman who, 1 day after suffering from fever, headache and malaise, developed a painful and swollen left knee. A maculopapular rash and the characteristic ‘tache noire’ skin lesion appeared 5 days later. Immune complexes were detected in serum and in the SF and normalized following improvement of clinic manifestations. These findings along with a low C3 complement level in the SF suggest that arthritis was mediated by immune complex deposits.Keywords
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