The Immunologic Response of Rabbits to Carrageenans, Sulfated Galactans Extracted from Marine Algae
Open Access
- 1 September 1968
- journal article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 101 (3) , 556-562
- https://doi.org/10.4049/jimmunol.101.3.556
Abstract
Summary: Both κ and λ carrageenans, sulfated galactans, elicit formation of precipitating antibodies in rabbits. The carrageenan-anti-carrageenan system follows the kinetics of other well-known antipolysaccharide systems. Both λ and κ carrageenan show a high degree of immunologic specificity; namely, no reaction was observed between antigen and heterologous antibody. Molecular weight determinations of the κ carrageenan antigen according to the Boyd and Hooker equation agree with molecular weights determined by other investigators: a value of 350,000 is calculated for the λ fraction.Keywords
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