Effects of Insulin and Gastro-Intestinal Hormones on Feeding and Plasma Insulin Levels in Sheep

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Abstract
Infusions of the following hormones were made into the hepatic vein of sheep over periods of 3 h: pentagastrin (2.1, 5.0 or 9.9 .mu.g/kg), pancreozymin (1.0 units/kg), secretion (2.0 units/kg), insulin (2.1 or 4.3 units/kg). Intake of the concentrate food was depressed by pentagastrin at 9.9 .mu.g/kg per 3 h (P < 0.05) and increased by insulin at 4.3 units/kg per 3 h (P < 0.05). Insulin levels in jugular plasma were unaffected by any of the gut hormone infusions. The liver is suggested as being involved in the control of food intake in sheep.

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