Decreasing Risk of Leukemia with Prolonged Follow-up after Chemotherapy and Radiotherapy for Hodgkin's Disease

Publisher Website
Google Scholar
Abstract
To the Editor: Blayney et al. (March 19 issue)1 have reported that the risk of leukemia decreases with prolonged follow-up after treatment of Hodgkin's disease. We have observed that leukemias also decline among long-term survivors of childhood cancer.Acute leukemia is one of the commonest second malignant neoplasms reported in patients who receive chemotherapy and radiotherapy for a childhood cancer.2 , 3 However, most secondary leukemias in these patients have developed within a decade after treatment. In 1973 a prospective study was initiated at the Dana–Farber Cancer Institute to examine the late occurrence of second primary cancers among persons who had survived . . .