An active-site titrant for chymotrypsin, and evidence that azapeptide esters are less susceptible to nucleophilic attack than ordinary esters
- 6 August 1996
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 6 (15) , 1771-1774
- https://doi.org/10.1016/0960-894x(96)00308-3
Abstract
No abstract availableKeywords
This publication has 13 references indexed in Scilit:
- 1-Acyl-2-alkylhydrazines by the Reduction of AcylhydrazonesSynthesis, 1995
- [6] Active-site titration of peptidasesPublished by Elsevier ,1995
- AzapeptidesSynthesis, 1989
- Dynamics at the active site of N2-acetyl-N1-(4-fluorobenzyl)carbazoyl-.alpha.-chymotrypsinJournal of the American Chemical Society, 1984
- A sensitive new substrate for chymotrypsinAnalytical Biochemistry, 1979
- Nα-ethyloxycarbonyl-α-azaornithine phenyl ester: a stable inhibitor of trypsin and thrombinTetrahedron, 1977
- Preparation and properties of some α-aza-amino-acid derivatives, their possible use in peptide synthesisTetrahedron, 1977
- The reaction of an α-aza-amino acid derivative with chymotrypsin and its use as a ligand for covalent affinity purificationBiochemical Journal, 1974
- 2 Chemical Modification by Active-Site-Directed ReagentsPublished by Elsevier ,1970
- Oxazolinone intermediates in the hydrolysis of activated N-acylamino acid esters. The relevance of oxazolinones to the mechanism of action of serine proteinasesBiochemistry, 1969