Serum Enzyme Activities Following Morphine
- 1 April 1962
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of internal medicine (1960)
- Vol. 109 (4) , 429-437
- https://doi.org/10.1001/archinte.1962.03620160055008
Abstract
An increase of serum glutamic oxalacetic transaminase (SGO-T) activity following myocardial infarction was first described by LaDue et al.1and subsequently confirmed by numerous investigators.2-6Much emphasis has been placed on elevated SGO-T values in substantiating the clinical impression of myocardial infarction, especially when the electrocardiogram reveals equivocal changes, previous infarction, left bundle branch block, or arrhythmia.7-9With increased understanding of the ubiquitous nature of GO-T distribution in human tissues, it has become apparent that liver necrosis10-14and a host of other disease states5,6,15-21can provoke a rise in SGO-T activity. Thus, confusion may still exist when there is elevated SGO-T activity in the absence of electrocardiographic evidence of heart muscle damage. Obstructive biliary tract disease causes a rise in SGO-T activity,22,23and this rise may be unrelated to hepatic necrosis.24The demonstration of high GO-T activity in bile25further serves toThis publication has 0 references indexed in Scilit: