Determination of the Primary Structure of a Mouse IgG2a Immunoglobulin
- 1 November 1975
- journal article
- Published by Wiley in European Journal of Biochemistry
- Vol. 59 (2) , 525-537
- https://doi.org/10.1111/j.1432-1033.1975.tb02479.x
Abstract
The amino acid sequence of the light chain of the mouse monoclonal MOPC 173 immunoglobulin molecule (IgG2a,chi) is presented. This kappa chain contains 214 residues. Comparisons of this sequence with murine kappa chains already published by other workers bring a confirmation of the large size of the murine V chi chain pool. A complete identity was found with the constant region of the light chain of MOPC 21 from residue 97 to residue 214.Keywords
This publication has 31 references indexed in Scilit:
- Determination of the Primary Structure of a Mouse IgG2a ImmunoglobulinEuropean Journal of Biochemistry, 1975
- Amino acid sequence of a murine immunoglobulin fragment that possesses complement fixing activityBiochemistry, 1974
- Determination of the Primary Structure of a Mouse IgG2a Immunoglobulin: Amino‐Acid Sequence of the Fc FragmentEuropean Journal of Biochemistry, 1974
- Mouse immunoglobulin chains. Survey of the amino-terminal sequences of κchainsBiochemistry, 1973
- Determination of the Primary Structure of a Mouse γG2a Immunoglobulin Identification of the Disulfide BridgesEuropean Journal of Biochemistry, 1972
- Variability of Interchain Binding of Immunoglobulins: Interchain Bridges of Mouse IgG2a and IgG2bNature, 1970
- Variability in the Lambda Light Chain Sequences of Mouse AntibodyNature, 1970
- Mechanism of Antibody Synthesis: Size Differences between Mouse Kappa ChainsScience, 1967
- An improved method of testing for evolutionary homologyJournal of Molecular Biology, 1966
- Variations in the heavy polypeptide chain structure of gamma myeloma immunoglobulins from an inbred strain of mice and a hypothesis as to their originJournal of Molecular Biology, 1965