Topiramate in Migraine Prevention

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Abstract
Migraine is a common, episodic, disabling disorder occurring in 17% of women, 6% of men, and 4% of children yearly.1 Approximately 53% of patients with severe migraines report that their attacks require bed rest or are a source of severe impairment.2 The cost of missed workdays and impaired performance because of migraine is estimated at $18 billion.1,2

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