ULTRASTRUCTURAL ORGANIZATION OF CANDIDA-ALBICANS BLASTOSPORE CELL-WALL - LOCALIZATION OF CHEMICAL AND ANTIGENIC COMPONENTS

  • 1 January 1981
    • journal article
    • research article
    • Vol. A132  (3) , 219-+
Abstract
The localization of chemical and/or antigenic components of C. albicans blastospore cell wall was studied. They concerned: PATAg reaction for the detection of polysaccharides on ultrathin sections associated with enzymatic digestions or polysaccharide extraction; the indirect immunoferritin method on intact cells; the indirect immunoperoxidase method on ultrathin section of water soluble embedding medium; the indirect immunofluorescence test, using patients and experimental sera. The cytochemical results confirmed a previously described 8 layer organization. The layer located near the plasmalemma must be considered as an important antigenic area. The mannans responsible for antigenic differences between strains of C. albicans and those supporting the serotype A activity were shown to be distributed among 2 of the described peripheral layers.

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