Stabilization of Urinary 3-Hydroxyanthranilic Acid by Oral Administration of L-Ascorbic Acid.
- 1 December 1967
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 126 (3) , 702-704
- https://doi.org/10.3181/00379727-126-32547
Abstract
Summary A method is presented for the stabilization of urinary 3-hydroxyanthranilic acid (3-HOA) to enable the acquisition of more reliable data concerning the urinary excretion of 3-HOA by patients with tumors of the urinary bladder. The data show that significant amounts of 3-HOA can decompose in urine samples of some tumor patients if such samples are allowed to incubate at 37°C for 6 hours, and that the presence of high levels of L-ascorbate in such samples inhibits this decomposition.Keywords
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