Effect of Aldrin on Carbohydrate Metabolism in Indian Catfish*

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Abstract
Exposure of the Indian catfish (H. fossilis) to a sublethal concentration of 0.14 ppm aldrin for 3, 6, 12, 48 and 96 h affected carbohydrate metabolism. Muscle glycogenolysis and glycogenesis were obtained at 3 and 12 h, respectively. Hepatic glycogenolysis occurred at 3, 48 and 96 h. Treatment caused hyperglycemia at 3, 6, 48 and 96 h and hypoglycemia at 12 h. Blood pyruvate values increased significantly at 3, 6 and 96 h. Hyperlacticemia was observed at 3 and 12 h but hypolacticemia developed at 96 h. Results were discussed in relation to acute stress syndrome. Impairment of carbohydrate metabolism by aldrin may be involved in the biochemical mechanism for its toxic action. Evaluation of carbohydrate metabolites in fish could prove useful as a rapid method for assessing acute toxicity of pesticides.