Gastric Carcinoma

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Abstract
Despite a marked decline in the incidence of gastric carcinoma in many industrialized nations, cancer of the stomach remains the second most common cause of cancer-related deaths in the world.1 In 1995, 22,800 Americans will be given a diagnosis of gastric carcinoma, and 14,700 will die of the disease.2 This review discusses recent developments in our understanding of the epidemiology and pathogenesis of gastric carcinoma, methods of diagnosis and staging, and approaches to treatment and palliation.Epidemiology and BiologyIncidenceIn 1930, gastric carcinoma was the leading cause of cancer-related deaths among American men and the third most common cause . . .