Circulatory and metabolic effects of acute beta1-blockade in severe pre-eclampsia
- 1 January 1979
- journal article
- research article
- Published by Wiley in Acta Obstetricia et Gynecologica Scandinavica
- Vol. 58 (5) , 443-445
- https://doi.org/10.3109/00016347909154064
Abstract
A beta1-adrenoceptor antagonist (atenolol, 5 mg) was given i.v. to 5 women with severe pre-eclampsia in the 3rd trimester of pregnancy. There was a significant decrease of mean systolic blood pressure, from 171-155 mm Hg, and mean diastolic blood pressure, from 116-107 mm Hg. The mean maternal heart rate decreased significantly from 90-74 and mean fetal heart rate significantly from 145-138 beats/min. There were no significant changes in the plasma levels of cyclic AMP, insulin, glucose, free fatty acids, 3-hydroxybutyrate or glycerol.This publication has 3 references indexed in Scilit:
- Propranolol therapy during pregnancy, labor, and delivery: Evidence for transplacental drug transfer and impaired neonatal drug dispositionThe Journal of Pediatrics, 1977
- Colorimetric micro-determination of free fatty acids in plasmaClinica Chimica Acta; International Journal of Clinical Chemistry, 1967
- An enzymatic fluorometric micromethod for the determination of glycerolClinica Chimica Acta; International Journal of Clinical Chemistry, 1966