AMIKACIN ASSAY - CORRELATION BETWEEN RAPID BIOASSAY, ENZYME IMMUNO-ASSAY (EMIT) AND FLUORO-IMMUNO-ASSAY (FIA)

  • 1 January 1984
    • journal article
    • research article
    • Vol. 42  (3) , 217-220
Abstract
Three methods (rapid bioassay, enzyme immunoassay [EMIT] and fluoroimmunoassay [FIA]) for the determination of amikacin level in serum are compared. The statistical analysis of the results show correlation coefficients equal to 0.967 (EMIT vs. FIA), 0.970 (bioassay vs. FIA) and 0.983 (bioassay vs. EMIT). The 3 methods are acceptable for routine clinical use. The enzyme immunoassay adapted on a centrifugal analyzer appears to be a method of choice for laboratories with a large workload. The rapid bioassay described remains adequate for laboratories testing 5-10 sera per day.

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