A NOVEL ETHYNYLATION OF α-SUBSTITUTED MESITYL OXIDES
- 5 August 1977
- journal article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 6 (8) , 943-946
- https://doi.org/10.1246/cl.1977.943
Abstract
The ethynylation of ketone (2) in liquid ammonia at −33°C with stoichiometric sodium acetylide afforded the corresponding alcohol (3 and 4). Similar treatment of 1 resulted in only a little isomerization to 2. Favorskii ethynylation under pressure at 0°C yielded a mixture of 1, 2, 3 and 4 without any detectable 5, whichever ketone 1 or 2 being used.This publication has 4 references indexed in Scilit:
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