Dapsone-Induced Distal Axonal Degeneration of the Motor Neurons

Publisher Website
Google Scholar
Abstract
Dapsone proved to be an effective treatment in a patient who suffered from erythema elevatum diutinum. Serious neurological side effects, however, appeared. The basic mechanism appeared to be a distal axonal degeneration of the motor neurons. Sensory conduction studies were normal in five consecutive EMG examinations. A diagnosis of anemia perniciosa was also made but the blood values returned to normal after starting B12-vitamin therapy. Pernicious anemia seemed not to be an etiological factor in the polyneuropathy of our patient because we were not able to show any damage to the sensory axons.

This publication has 0 references indexed in Scilit: