Tetanus

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Abstract
THE etiologic agent of tetanus is an anaerobic spore-forming rod, Clostridium tetani. None of the clinical manifestations of the disease are produced by tissue injury but result from the activity of a soluble exotoxin, tetanospasmin, which is elaborated at the site of injury by vegetative forms of the organism. Tetanus, usually an infrequent disorder in the well developed parts of the world, is common in some underdeveloped countries. Cl. tetani, in the vegetative form, is a gram-positive, slender motile rod. The sporulated form is characteristically drumstick or tennis racket in appearance, with the spore at the terminal end . . .