Cases of purpura fulminans have been so rarely reported and so little is known as to its clinical manifestations and causation that I feel no hesitation in publishing an account of the following case, especially since the general question of hemolysis is at present attracting so much attention, and the etiologic factor back of this unusual affection appears to be one of hemolytic nature. Case History Patient.—Helen M., aged 8 years, 7 months. Mother and father living and well. No brothers or sisters. One uncle died of tuberculosis of the lungs. Otherwise the family history is negative. No history of purpura or of "bleeders" in the family. Previous Illnesses.—The patient had whooping cough at 3; she was sick two months; measles and chickenpox in her seventh year, both light attacks. She was never a robust child, but was always healthy, aside from the above acute