INVITRO KILLING OF PASTEURELLA-MULTOCIDA - EFFECT OF RABBIT GRANULOCYTE AND SPECIFIC ANTIBODY SOURCE

  • 1 January 1979
    • journal article
    • research article
    • Vol. 40  (5) , 679-683
Abstract
In vitro granulocyte-killing assays were performed to examine the ability of granulocytes from Pasteurella-free or immunized rabbits, in combination with specific immune serum, to kill P. multocida. Granulocytes from healthy rabbits and from rabbits with P. multocida infections were equally competent. Granulocyte source, serum source and specific antibody [Ab] titer had no effect on granulocyte phagocytic activity. Serum containing specific Ab and complement supported the growth of the bacterium. Chronic P. multocida infections are not attributable to defective granulocytes or lack of serum Ab production.