Transgenic Overexpression of β2-Adrenergic Receptors in Airway Smooth Muscle Alters Myocyte Function and Ablates Bronchial Hyperreactivity
Open Access
- 1 November 1999
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 274 (45) , 32241-32247
- https://doi.org/10.1074/jbc.274.45.32241
Abstract
No abstract availableKeywords
This publication has 21 references indexed in Scilit:
- Expression of a β-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted miceProceedings of the National Academy of Sciences, 1998
- Role of βARK in Long-Term Agonist-Promoted Desensitisation of the β2-Adrenergic ReceptorCellular Signalling, 1998
- Targeted overexpression of IGF-I evokes distinct patterns of organ remodeling in smooth muscle cell tissue beds of transgenic mice.Journal of Clinical Investigation, 1997
- Heterogeneity in β-Adrenergic Receptor Kinase Expression in the Lung Accounts for Cell-specific Desensitization of the β2-Adrenergic ReceptorPublished by Elsevier ,1997
- Regulation of cellular Gs? levels and basal adenylyl cyclase activity by expression of the ?2-adrenoceptor in neuroblastoma cell linesMolecular and Cellular Biochemistry, 1995
- Enhanced Myocardial Function in Transgenic Mice Overexpressing the β 2 -Adrenergic ReceptorScience, 1994
- Distribution of β1‐ and β2‐adrenoceptors in mouse trachea and lung: a quantitative autoradiographic studyBritish Journal of Pharmacology, 1990
- β1‐Adrenoceptors mediate smooth muscle relaxation in mouse isolated tracheaBritish Journal of Pharmacology, 1990
- Are receptors promiscuous? Intrinsic efficacy as a transduction phenomenonLife Sciences, 1988
- An examination of some β-adrenoreceptor stimulants for selectivity using the isolated trachea and atria of the guinea pigEuropean Journal of Pharmacology, 1972