Remarkable Enhancement of Lipase Catalytic Activity: Combined Effects of Acyl Donor and Thiacrown Ether Additive during Trans-esterification of 5-Phenyl-1-penten-3-ol
- 1 December 1997
- journal article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 26 (12) , 1247-1248
- https://doi.org/10.1246/cl.1997.1247
Abstract
The Pseudomonas cepacia lipase-catalyzed trans-esterification of 5-phenyl-1-penten-3-ol was drastically accelerated by 5 mol% of a thiacrown ether additive. The reaction profile was strongly dependent on the nature of the vinyl esters as the acyl donor; the highest acceleration rate was recorded with vinyl chloroacetate, while the highest enantioselectivity was obtained using vinyl acetate.Keywords
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