Sensitization of Combined cis-Platinum and Cyclophosphamide by Local Hyperthermia in Mice bearing the Lewis Lung Carcinoma
- 1 January 1984
- journal article
- research article
- Published by S. Karger AG in Oncology
- Vol. 41 (1) , 68-69
- https://doi.org/10.1159/000225794
Abstract
The combined effect of cis-platinum cyclophosphamide, and local hyperthermia was investigated in mice bearing the metastatic Lewis lung carcinoma. The combined action of cyclophosphamide and cis-platinum resulted in an additive effect. The triple combination of cis-platinum, cyclophosphamide and local hyperthermia revealed thermal potentiation of the combined drug-induced growth delay.Keywords
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