Influence of Phosphoserine on the Performance of Rats on the Rotarod
- 1 January 1976
- journal article
- research article
- Published by S. Karger AG in Pharmacology
- Vol. 14 (1) , 52-57
- https://doi.org/10.1159/000136579
Abstract
The anti-fatigue effect of phosphoserine, L-serine and a mixture of sodium phosphate and L-serine was studied in rats. Phosphoserine orally administered induced a statistically significant anti-fatigue effect in rats of both sexes submitted to a training test by rotarod, with 14 sessions in 3 days. Phosphoserine was utilized better than the mixture of sodium phosphate and L-serine, where L-serine alone induced no effect. Therefore, the effect of phosphoserine seems to be due to the phosphoryl bond.Keywords
This publication has 3 references indexed in Scilit:
- Mouse Brain Phosphoserine Phosphohydrolase and PhosphotransferaseJournal of Biological Chemistry, 1967
- The incorporation of the phosphate esters of N-substituted aminoethanols into the phospholipids of brain and liverBiochemical Journal, 1966
- Metabolism of phospholipids VI. The effect of metal ions on the incorporation ofl-serine into phosphatidylserineBiochimica et Biophysica Acta, 1962