(p-Dimethylaminophenyl) Diphenylphosphine: A More Practical Phosphine in the Mitsunobu Reaction
- 1 July 1990
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 20 (13) , 2049-2057
- https://doi.org/10.1080/00397919008053136
Abstract
The Mitsunobu reaction has been of much use in general synthetic organic chemistry. The major drawback of this reaction has been the removal of the by-products triphenylphosphine oxide and the dialkyl hydrazinedi-carboxylate. We report here that (p-dimethylaminophenyl)diphenylphosphine, an alternative phosphine, greatly assists the work-up procedure of this useful reaction.Keywords
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