Polycystic Kidney Disease -- There Goes the Neighborhood

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Abstract
Renal cysts look innocent enough. When they occur alone, as they commonly do in adults over the age of 50 years, they do no harm. The handiwork of the aging process, some would have you believe. But when they appear in the kidneys in large numbers, as in patients with autosomal dominant polycystic kidney disease, renal cysts can lead to the destruction of renal parenchyma and to chronic renal failure. Autosomal dominant polycystic kidney disease is the most common monogenic disorder that is potentially fatal. Each year nearly a billion dollars is expended in the treatment of patients with the . . .