Inhibitory metabolite complex formation of methylenedioxymethamphetamine with rat and human cytochrome P450. Particular involvement of CYP 2D

This publication has 20 references indexed in Scilit:

• d-Amphetamine-induced hepatotoxicity: possible contribution of catecholamines and hyperthermia to the effect studied in isolated rat hepatocytes
  Archives of Toxicology, 1997
• Differential Regulation by Methylenedioxymethamphetamine of 5‐Hydroxytryptamine_1A Receptor Density and mRNA Expression in Rat Hippocampus, Frontal Cortex, and Brainstem: The Role of Corticosteroids
  Journal of Neurochemistry, 1997
• Chronic ecstasy (3,4-methylenedioxymetamphetamine) abuse: a recurrent and unpredictable cause of severe acute hepatitis
  Journal of Hepatology, 1996
• Acute liver damage and ecstasy ingestion.
  Gut, 1996
• Psychobiologic effects of 3,4-methylenedioxymethamphetamine in humans: methodological considerations and preliminary observations
  Behavioural Brain Research, 1995
• Review of the pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA or “Ecstasy”)
  Psychopharmacology, 1995
• Particular ability of cytochromes P450 3A to form inhibitory P450-iron-metabolite complexes upon metabolic oxidation of aminodrugs
  Biochemical Pharmacology, 1995
• The substituted amphetamines 3,4-methylenedioxymethamphetamine, methamphetamine, p-chloroamphetamine and fenfluramine induce 5-hydroxytryptamine release via a common mechanism blocked by fluoxetine and cocaine
  European Journal of Pharmacology, 1992
• Debrisoquine 4-Hydroxylase: Characterization of a New P450 Gene Subfamily, Regulation, Chromosomal Mapping, and Molecular Analysis of the DA Rat Polymorphism
  DNA, 1987
• Ligand-complex formation between cytochromes P-450 and P-448 and methylenedioxyphenyl compounds
  Xenobiotica, 1985