Synthesis Routes Towards the Farnesyl Protein Transferase Inhibitor ZARNESTRA^TM

This publication has 15 references indexed in Scilit:

• R-115777
  Drugs of the Future, 2001
• Farnesyl Transferase Inhibitors Block the Farnesylation of CENP-E and CENP-F and Alter the Association of CENP-E with the Microtubules
  Journal of Biological Chemistry, 2000
• Carboxylate Protection for the Synthesis of 4,5-Disubstituted 1-Methylimidazoles
  The Journal of Organic Chemistry, 1994
• Synthesis of 2,5-dilithio-1-methylimidazole
  Tetrahedron Letters, 1993
• Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides
  Cell, 1990
• Acylation of ester enolates by N-methoxy-N-methylamides: an effective synthesis of .beta.-keto esters
  The Journal of Organic Chemistry, 1989
• High frequency of Ki‐ras codon 12 mutations in pancreatic adenocarcinomas
  International Journal of Cancer, 1989
• Expression of ras p21 Oncogene Product on Human Bladder Tumors
  Urologia Internationalis, 1989
• Detection of high incidence of K-ras oncogenes during human colon tumorigenesis
  Nature, 1987
• Benzoylation of Halobenzenes Catalysed by Iron(III) Sulphate
  Synthesis, 1977