STUDIES IN ISOUREAS AND ISOUREIDES: V. THE ADDITION OF DIHYDRIC AND SUBSTITUTED ALCOHOLS TO CYANAMIDE

Abstract
In continuation of earlier studies on the formation of alkyl-isoureas by the addition of alcohols to cyanamide, a series of new isoureas has been prepared from ethylene glycol, glycol mono-ethyl ether, glycol mono-acetate, ethyl glycollate, ethanolamine, and resorcinol. In addition, the preparation of allyl-isourea, which had previously failed, m-nitrobenzyl- and cyclohexyl-isoureas was accomplished. The new isoureas were characterized by the preparation of salts (salicylates or benzoates), and of cyclic isoureides by condensation with acetoacetic and malonic esters. Some further study was made of benzyl- and phenylethyl-isoureas, previously prepared in this laboratory.

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