AVITAMINOSIS
- 1 March 1932
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of internal medicine (1908)
- Vol. 49 (3) , 397-404
- https://doi.org/10.1001/archinte.1932.00150100054003
Abstract
In previous communications we have demonstrated that the main biochemical changes in the albino rat suffering from a deficiency of the vitamin B complex are anhydremia associated with a disturbance in hematopoietic function1and, in uncomplicated vitamin B deficiency, a marked reduction in the glycogen content of the liver.2Since in such avitaminosis the most pronounced symptom complex is anorexia, the tentative conclusion made was that the pathologic changes encountered may have been, at least in part, produced indirectly through a reduction in food consumption. In this and in the communication following, experimental evidence is submitted on studies carried out by a method which eliminated the plane of nutrition as a complicating factor. Weaned albino rats, weighing from 50 to 60 Gm. and about 4 weeks of age, were transferred from our stock diet 13to diet 1751, satisfactory in every respect, with the exception of vitaminThis publication has 0 references indexed in Scilit: